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Extreme Weight Conditions In Women May Increase Likelihood Of Mood Disorders

Women often feel like they “can’t win” when it comes to their weight, size, and appearance in the eyes of others. We’re either too overweight or we are too thin and the judgements come from everywhere- our friends, our family, our fashion stores, our media, and more. Women strive to learn how to maintain a state of health that works in their best interest, for them alone. We have learned through extensive genetic research that some women are naturally low weight and some are naturally higher weight. Problematically, the perpetuation of an ‘ideal’ weight and body type negates the very real circumstance of genetics and the uniqueness of every woman’s body. However, it is important to take science into consideration and work with medical, as well as holistic professionals, to find the state of health that supports longevity, quality of life, and holistic wellness of mind, body, and spirit.

Recently, scientific research discovered that women who are on the extremes of weight, either underweight or overweight, have a greater likelihood of developing a mood disorder like depression or anxiety. A neuroactive steroid is the cause of this development, according to the study by Harvard Medical School. The study was published in Neuropsychopharmacology.

The Health Site reports that “Neurosteroid ‘Allopregnanolone’ also known as ‘allo’ is a metabolite of the hormone progesterone — a female hormone.  Allo works by producing a positive mood and feelings of well-being.” Women with the eating disorder anorexia nervosa, which caused them to be underweight, had 50% less allo in their blood. On the other hand, women who were clinically obese had 60% less allo levels in their blood.

Developing treatments to target this specific steroid will be helpful in balancing mood in women recovering from anorexia, or working toward better health. Treatment for women with mood disorders should be holistic in nature, taking into consideration the mind, body, and spirit. Anxiety and depression are commonly co-occurring with substance use disorders, which can also be co-occurring with eating disorders of varying kind. Women deserve the best in health, treatment, and recovery.


Compassionate, authentic, serene. Villa Tranquil Recovery offers women between the ages of 18-65 a unique opportunity for a safe, structured, and supportive transitional living program after primary treatment. Located in the quiet beauty of Jupiter Farms, Florida, women in our program continue to grow and develop, learning how to live a thriving and fulfilling life in sobriety. Call us today for information:  214-799-3080